Diverse Physiological Functions of MKK4 and MKK7 during Early Embryogenesis
نویسندگان
چکیده
منابع مشابه
Assessing developmental roles of MKK4 and MKK7 in vitro
In vivo gene knockout studies in mice have revealed essential roles of the mitogen-activated protein kinases (MAPKs) in embryogenesis, but due to early lethality of the knockout embryos, the underlying mechanisms and specific developmental programs regulated by the MAPK pathways have remained largely unknown. In vitro differentiation of mouse embryonic stem cells (ESCs) have opened new possibil...
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ژورنال
عنوان ژورنال: Journal of Biochemistry
سال: 2010
ISSN: 0021-924X
DOI: 10.1093/jb/mvq098